Intramolecular folding in three tandem guanine repeats of human telomeric DNAw
نویسندگان
چکیده
Intramolecular folding in three tandem guanine repeats of human telomeric DNA has been investigated using opticaltweezers, MD simulation and circular dichroism. A mechanically and thermodynamically stable species in this sequence shows a structure consistent with a triplex conformation. A similar species has also been observed to coexist with a G-quadruplex in a DNA sequence with four tandem guanine repeats.
منابع مشابه
Intramolecular folding in three tandem guanine repeats of human telomeric DNA.
Intramolecular folding in three tandem guanine repeats of human telomeric DNA has been investigated using optical-tweezers, MD simulation and circular dichroism. A mechanically and thermodynamically stable species in this sequence shows a structure consistent with a triplex conformation. A similar species has also been observed to coexist with a G-quadruplex in a DNA sequence with four tandem g...
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